What happens when a worker at a lab that studies plague dies, and no one will say why? A 28-year-old researcher at Russia’s Irkutsk Anti-Plague Research Institute has died of pneumonia of unknown cause. Russian officials say there is no epidemic risk, yet they quarantined more than 200 of her contacts and have not shared key details such as the pathogen’s genome sequence. As epidemiologist Jennifer Nuzzo put it, “Something is not adding up about this situation.” The case is a reminder that biosafety in high-risk labs is a global security issue, and that transparency matters when something goes wrong. Read more here.